Search results for "cell-cell communication"

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Extracellular vesicles from PBDE-47 treated M(LPS) THP-1 macrophages modulate the expression of markers of epithelial integrity, EMT, inflammation an…

2023

Aims: The lung epithelial cells form a physical barrier to the external environment acting as the first line of defence against potentially harmful environmental stimuli. These cells interact with several other cellular components, of which macrophages are some of the most relevant. We analysed the effects of the PBDE-47 on the microRNA cargo of THP-1 macrophage like derived small Extracellular Vesicles (sEVs) and the effects on A549 lung epithelial cells. Main methods: sEVs from M(LPS) THP-1 macrophage-like cells after PBDE-47 treatment (sEVsPBDE+LPS) were characterized by nanoparticle tracking analysis and their microRNA cargo studied by qPCR. Confocal microscopy was applied to study sEVs…

Epithelial cellMacrophagesAirway diseaseGeneral MedicineCell-cell communicationGeneral Pharmacology Toxicology and PharmaceuticsGeneral Biochemistry Genetics and Molecular BiologyLife Sciences
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Autophagy Induces Expression of IL-6 in Human Periodontal Ligament Fibroblasts Under Mechanical Load and Overload and Effects Osteoclastogenesis in v…

2021

Frontiers in physiology 12, 716441 (2021). doi:10.3389/fphys.2021.716441 special issue: "Alveolar Bone: a Pivotal Role in Periodontal Disease Pathobiology and Treatment, Volume I / Fani Anagnostou, Beatriz Castaneda, Frédéric Lézot and Petros Papagerakis"

Mechanical overloadautophagymechanical loadPhysiologymedicine.medical_treatmentADAM10Matrix metalloproteinaseOsteoprotegerinhuman periodontal ligament fibroblastsPhysiology (medical)medicineQP1-981cell-cell communicationOriginal ResearchIL-6ADAM17biologyChemistryAutophagyADAM10OsteoblastCell biologymechanical overloadCytokinemedicine.anatomical_structureRANKLbiology.proteinFrontiers in Physiology
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